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Pharma

Once-weekly drug for Parkinson’s disease symptoms could reach clinical trials in 2013

A drug for Parkinson’s disease that could ease some of the complications associated with current dopamine replacement therapies could reach clinical trials next year. Serina Therapeutics’ platform technology is based on the polymer polyoxazoline (POZ), which the company is pairing with rotigotine (a dopamine agonist also used UCB’s FDA-approved Neupro patch) to create a once-weekly […]

Pharma

Head and neck cancer treatment combines enzyme, existing drugs to make tumors self-destruct

A clinical-stage biopharmaceutical company is testing a new targeted cancer treatment based on the notion that solid tumors can be compelled to develop their own chemotherapy and self-destruct. In PNP Therapeutics Inc.’s platform technology, an E. coli purine nucleoside phosphorylase (PNP) gene injected directly into a tumor produces enzymes that interact with a circulating prodrug, […]